Main Page
About the Journal
Subscription information

Current Issue
Tables of Contents
Author Index


Ferrifluids cytotoxity excitation by an AC magnetic field

N. A. Brusentsov1 - E. Yu. Filinova1 - T. G. Nikolaeva1 - A. Yu. Baryshnikov1 - V. V. Gogosov2 - T. N. Brusentsova2 - L. Kh. Komissarova3 - A. F. Mirognov4 - A. V. Lubeshkin4 - L. I. Shumakov5

1 Russian N.N. Blokhin Memorial Cancer Research Center RAMS, Moscow, Russia
2 Institute of Mechanics, Moscow State University, Moscow, Russia
3 Institute of Biochemical Physics RAS, Moscow, Russia
4 Lomonosov State Academy of Fine Chemical Technology, Moscow, Russia
5 All-Russian Radiotechnical Research Institute, Moscow, Russia

The tumor cells murine ascitic limpholeukosis and adherent human carcinoma ovarii alone and with reagents (dextran-ferrite, photogem, histidine, and its combinations) were placed in the center of a coil and exposed to the AC magnetic field in the dark for AC induction hyperthermia and magnetosensitization. A count of the viable cells under different conditions (magnetosensitization, temperature, photogem concentration, and so forth) were investigated. The AC magnetic field cells damage enhancement by photogem at +37°C and simultaneous thermal- and AC magnetic field cell damage enhancements by photogem at +41°C were effectively suppressed by adding an singlet oxygen scavenger, histidine. Tables 6, Figs 3, Refs 17.

Magnetohydrodynamics 38, No. 4, 399-408, 2002 [PDF, 0.29 Mb]

Copyright: Institute of Physics, University of Latvia
Electronic edition ISSN 1574-0579
Printed edition ISSN 0024-998X